Contact Information
Address: 443 Huangshan Road, Hefei, Anhui 230027
Tel: 86-551-63607141
Fax: 86-551-63607141
E-mail: xing1017@ustc.edu.cn
Lab website: faculty.ustc.edu.cn/liuxing1/en/index.htm
ORCID: https://orcid.org/0000-0002-7480-5085
Education and Research Experience
2019-present Professor, University of Science and Technology of China
2016-2019 Associate Professor, University of Science and Technology of China
2014-2016 Postdoc, Hefei National Laboratory for Physical Sciences at the Microscale
2008-2014 Ph.D., University of Science and Technology of China
2004-2008 B.S., Anhui University
Research Interests
Chemical biology of mitosis
Cell division control on organoids
Super-resolution imaging
Selected Publications
1. Zhang T#, Liu S#, Durojaye O, Xiong F, Fang Z, Ullah T, Fu C, Sun B, Jiang H, Xia P, Wang Z*, Yao X*, Liu X*. Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation. Cell Rep. 2024 Sep 24;43(9):114739.
2. Dou Z#, Liu R#, Gui P#, Fu C, Lippincott-Schwartz J, Yao X*, Liu X*. Fluorescence complementation-based FRET imaging reveals centromere assembly dynamics. Mol Biol Cell. 2024 Apr 1;35(4):ar51.
3. Song X#, Yang F#, Yang T#, Wang Y#, Ding M#, Li L#, Xu P, Liu S, Dai M, Chi C, Xiang S, Xu C, Li D, Wang Z, Li L, Hill DL, Fu C, Yuan K, Li P, Zang J, Hou Z, Jiang K, Shi Y, Liu X*, Yao X*. Phase separation of EB1 guides microtubule plus-end dynamics. Nat Cell Biol. 25(1):79-91. (2023) (Highlighted by Nature Cell Biology)
4. Liu S, Yuan X, Gui P, Liu R, Durojaye O, Hill DL, Fu C, Yao X*, Dou Z*, Liu X*. Mad2 promotes Cyclin B2 recruitment to the kinetochore for guiding accurate mitotic checkpoint. EMBO Rep. 23(6):e54171. (2022)
5. Song X#, Yang F#, Liu X#, Xia P#, Yin W, Wang Z, Wang Y, Yuan X, Dou Z, Jiang K, Ma M, Hu B, Zhang R, Xu C, Zhang Z, Ruan K, Tian R, Li L, Liu T, Hill DL, Zang J*, Liu X*, Li J*, Cheng J*, Yao X*. Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis. Nat Chem Biol. 17(12):1314-1323. (2021) (Highlighted by Nature Chemical Biology)
6. Xu L#, Ali M#, Duan W#, Yuan X*, Garba F, Mullen M, Sun B, Poser I, Duan H, Lu J, Tian R, Ge Y, Chu L, Pan W, Wang D, Hyman A, Green H, Li L, Dou Z*, Liu D*, Liu X*, Yao X*. Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation. Cell Rep. 36(2):109343. (2021)
7. Tang R#, Jiang Z#, Chen F#, Yu W, Fan K, Tan J, Zhang Z, Liu X*, Li P, Yuan K*. The Kinase Activity of Drosophila BubR1 Is Required for Insulin Signaling-Dependent Stem Cell Maintenance. Cell Rep. 31(12):107794.(2020)
8. Liu X, Liu X, Wang H, Dou Z, Ruan K, Hill DL, Li L, Shi Y, Yao X*. Phase separation drives decision making in cell division. J Biol Chem. 295(39):13419-13431. (2020) Review. (Recommended by F1000)
9. Huang Y#, Lin L#, Liu X#, Ye S#, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang Y, Zhang J, Yang Z, Liu X, Yang Z, Zang J, Teng M, Wang Z, Ruan K, Ding X, Li L, Cleveland DW, Zhang R*, Yao X*. BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res. 29(7):562-578. (2019) (Highlighted by Cell Research)
10. Akram S#, Yang F#, Li J#, Adams G, Liu Y, Zhuang X, Chu L, Liu X, Emmett N, Thompson W, Mullen M, Muthusamy S, Wang W, Mo F*, Liu X*. LRIF1 interacts with HP1α to coordinate accurate chromosome segregation during mitosis. J Mol Cell Biol. 10(6):527-538. (2018)
11. Mo F#, Zhuang X#, Liu X*, Yao PY, Qin B, Su Z, Zang J, Wang Z, Zhang J, Dou Z, Tian C, Teng M, Niu L, Hill DL, Fang G, Ding X, Fu C, Yao X*. Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation. Nat Chem Biol. 12(4):226-32. (2016) (Highlighted by Nature Chemical Biology)
Honors and Awards
Journal of Molecular Cell Biology Early - Career Guest Editor (2021-present)
Molecular Biology of the Cell - Associate Editor (2024-present)
Cell Biology International - Associate Editor (2024-present)
The International Collaboration Committee co-chair of Chinese Society for Cell Biology (2023-present)
2021 Journal of Molecular Cell Biology JMCB 2021 Best Editor Award
2022 USTCAF Young Faculty Career Award