PhD Supervisor, Chief Physician of the Hematology Department at the First Affiliated Hospital of the University of Science and Technology of China, Doctor of Clinical Medicine, Postdoctoral Supervisor, and the seventh batch of Academic and Technical Leaders in Anhui Province.
Education and Work Experience
- 1994–1999: Bachelor's Degree in Clinical Medicine, Anhui Medical University
- 2005–2008: Master’s Degree in Internal Medicine (Hematology), Anhui Medical University
- 2011–2014: PhD in Internal Medicine (Hematology), Shandong University
- 1999–2005: Resident and Chief Resident, Hematology Department, Anhui Provincial Hospital
- 2005–2011: Attending Physician and Lecturer, Hematology Department, Anhui Provincial Hospital
- 2011–2017: Associate Chief Physician and Associate Professor, Hematology Department, Anhui Provincial Hospital
- 2017–Present: Chief Physician, Hematology Department, First Affiliated Hospital of USTC
Academic Achievements and Impact
Possesses a solid and comprehensive foundation in internal medicine and hematology clinical practice and theory. Has conducted in-depth research in bleeding and coagulation disorders, malignant hematological diseases (including recurrent and refractory leukemia and MDS, lymphoma, and myeloma), hematopoietic stem cell transplantation (especially cord blood transplantation), and severe infections in hematological diseases. Currently serves as a director of the Asia-Pacific Medical Biochemistry Immunology Society, an executive member of the Hematology Branch of the Asia-Pacific Medical Biochemistry Immunology Society, a member of the Thrombosis and Hemostasis Group of the Hematology Branch of the Chinese Medical Association, an expert committee member of the Chinese Myelodysplastic Syndrome and Myeloproliferative Neoplasms Working Group, an expert committee member of the China Hemophilia Gene Bank Management Committee, and a member of the Platelet Disease Committee of the Hematology Branch of the Chinese Geriatrics Society. Also serves as an evaluation expert for the Academic Degrees Center of the Ministry of Education, an editorial board member of the journal Thrombosis and Hemostasis, and has received the 16th Anhui Youth Science and Technology Award and the Anhui May 1st Labor Medal. Has won two second prizes of the Anhui Science and Technology Award (for bleeding disorders and hematopoietic stem cell transplantation). In recent years, as the principal investigator, has led several research projects funded by the National Natural Science Foundation of China, Central Universities' Basic Scientific Research Fund, Anhui Natural Science Foundation, and Anhui Key Research and Development Program.
Has published over 50 papers as the first or corresponding author in renowned international SCI journals such as Haematologica, British Journal of Haematology, American Journal of Hematology, Annals of Hematology, Biology of Blood and Marrow Transplantation (BBMT), and Bone Marrow Transplantation (BMT), as well as in core domestic journals. Contributed to the formulation of the international guideline Chinese Guidelines for Treatment of Adult Primary Immune Thrombocytopenia.
Ongoing Projects (Principal Investigator Only)
| Project Name | Source | Funding ID | Total Funding (10,000 RMB) | Duration |
| Establishment and Application of a Key Clinical System for CD33-CLL1 Dual-Target Chimeric Antigen Receptor T Cell Therapy for Acute Myeloid Leukemia (202004j07020025) | Anhui Key Research and Development Program | 30 | 2020-01 to 2022-12 |
Main Research Directions (Recruitment Specialties) and Content
Clinical Medicine
1. Internal Medicine (Hematology)
- Diagnosis and treatment of malignant hematological diseases
- Mechanism research of thrombocytopenic diseases
- Mechanism research of GVHD and GVL separation in hematopoietic stem cell transplantation
Representative Papers (Last Five Years)
1. Xinhui Zhang, Shanglong Feng, Jin Xu, Na Zhao, Xing Hu, Li Zhou, Juan Tong, Lei Xue, Lei Zhang, Yongsheng Han, Xingbing Wang, Liangquan Geng, Xiaoyu Zhu, Baolin Tang, Huilan Liu, Weibo Zhu, Xiaoyan Cai, Xin Liu, Zimin Sun, Changcheng Zheng (Correspondence); All-trans retinoic acid 45mg/m² is superior to 25mg/m² as the first induction regimen for the treatment of acute promyelocytic leukemia: a retrospective analysis in a real-world clinical setting. Blood Cancer J. 2021; 11, 15.
2. Xu J, Zhang X, Feng S, Zhao N, Hu X, Cheng Y, Wu Y, Zhou L, Tong J, Zheng C (Correspondence). Clinical efficacy of high-dose dexamethasone with sequential prednisone maintenance therapy for newly diagnosed adult immune thrombocytopenia in a real-world setting. J Int Med Res. 2021 Apr;49(4):3000605211007322.
3. Lin X, Xu A, Zhou L, Zhao N, Zhang X, Xu J, Feng S, Zheng C (Correspondence). Imbalance of T Lymphocyte Subsets in Adult Immune Thrombocytopenia. Int J Gen Med. 2021 Mar 18;14:937-947.
Contact Information
E-mail: zhengchch1123@ustc.edu.cn
Phone: 0551-62282953