PhD supervisor, Doctor of Medicine, Chief Technician and Professor at the First Affiliated Hospital of University of Science and Technology of China, Deputy Director of the Department of Laboratory Medicine, a recipient of the Anhui Province's fifth Special Support Plan for innovative leading talents, an academic and technical leader in the eighth batch of Anhui Province, and a young leading talent in the first batch of the Anhui health system. Serves as a member of the Cell Analysis Committee of the Chinese Society of Biomedical Engineering, a member of the Clinical Medicine Professional Committee of the Chinese Society of Biochemistry and Molecular Biology, the incoming director of the Clinical Immunology Branch of the Anhui Medical Association, the vice president of the Point-of-Care Testing Medical Branch of the Anhui General Practitioners Association, a standing committee member of the Clinical Laboratory Management Professional Committee of the Anhui Hospital Association, a director of the Anhui Cell Biology Association, a member of the Australian Chinese Biomedical Science Association, a reviewer for the National Natural Science Foundation, and a reviewer for the Academic Degrees Committee of the Ministry of Education. Awards include one third prize in Natural Science and two third prizes in Science and Technology from Anhui Province.
Education
- 2000-2003: Master of Medicine in Clinical Laboratory Diagnostics, Bengbu Medical College
- 2007-2010: Doctor of Medicine in Pharmacology, Anhui Medical University
- 2014-2015: Visiting Scholar, Westmead Institute for Medical Research, University of Sydney, Australia
Work Experience
- 2003-2005: Technician, Anhui Provincial Hospital
- 2005-2010: Supervising Technician, Anhui Provincial Hospital
- 2010-2016: Associate Chief Technician, Anhui Provincial Hospital
- 2016-2017: Chief Technician, Anhui Provincial Hospital
- 2017-present: Chief Technician and Professor, The First Affiliated Hospital of the University of Science and Technology of China (Anhui Provincial Hospital)
Academic Achievements and Impact
Dedicated to teaching and scientific research in clinical laboratory diagnostics for over two decades, the focus has been on the cellular immunological mechanisms underlying atherosclerosis and related cardiovascular and cerebrovascular diseases, the identification of new markers for early diagnosis and prognosis evaluation of these conditions, and the investigation of therapeutic targets for interventional treatments. Over twenty doctoral and master's students have been mentored in this field.
Has presided over more than ten national and provincial scientific research projects, including the National Natural Science Foundation of China (82372302, 81472018), the Key Research and Development Plan of Anhui Province (201904b11020045), and the General Program of the Natural Science Foundation of Anhui Province (2208085MH228, 1408085MH145). Has received one third prize in natural science and two third prizes in scientific and technological progress from Anhui Province.
Published over 40 SCI papers in authoritative academic journals in the field, and served as an editor for several English-language journals and a reviewer for SCI journals.
Ongoing Research Projects (Limited to Principal Investigator)
The first project, supported by the People's Government of Anhui Province, is the Anhui Province Special Support Plan for Health Innovation Leadership Talents project. The project is funded with a budget of 500,000 CNY from January 2020 to December 2025
The second project, a general project of the Anhui Provincial Natural Science Foundation, investigates the mechanism of macrophage membrane-coated novel nanomaterials in treating reperfusion injury in acute ischemic stroke. The project is funded with a budget of 100,000 CNY and is scheduled from January 2022 to December 2024.
The third project, a general project of the National Natural Science Foundation of China, investigates the mechanism by which NPTX1 promotes vascular endothelial cell senescence in atherosclerosis and its clinical value,receiving 490,000 CNY from January 2024 to December 2027.
Main Research Directions (Enrollment Specialties) and Content
Biology
1. Cell Biology
- Research on the cellular biological mechanisms of atherosclerosis
- Research on endothelial cell senescence mechanisms
Clinical Medicine
1. Clinical Laboratory Diagnostics
- Cellular immunological mechanisms of atherosclerosis and related cardiovascular and cerebrovascular diseases
- Screening new indicators for early diagnosis and prognosis evaluation of cardiovascular and cerebrovascular diseases.
- Research on intervention treatment targets for cardiovascular and cerebrovascular diseases
Representative Papers (Last Five Years)
1. Li Q#, Cao Q#, Wang C, Nguyen H, Wang XM, Zheng G, Wang YM, Hu S, Alexander SI, Harris DCH, Wang Y*. Dendritic cell-targeted CD40 DNA vaccine suppresses Th17 and ameliorates progression of experimental autoimmune glomerulonephritis. J Leukoc Biol. 2019; 105(4):809-819.
2. Deng J#, Fu R#, Li Q*, Wang Y, Hu W*, Shen B, Li H, Hu C, Liu M, Zhang L, Liu M, Cao Q, Wang Y. Increased sFRP3 expression correlated to senescence of endothelial cells in the aging process of mice. Am J Transl Res. 2019; 11(3):1810-1818.
3. Zhang L, Liu M, Li Q*, Shen B, Hu C, Fu R, Liu M, Deng J, Cao Q, Wang Y, Wang Y. Identification of differential gene expression in endothelial cells from young and aged mice using RNA-Seq technique. Am J Transl Res. 2019; 11(10):6553-6560.
4. Li Q#*, Liu M#, Fu R#, Cao Q#, Wang Y, Han S, Hu W, Li H, Hu C, Wu L, Zhang L, Deng J, Wang Y. Alteration of circulating innate lymphoid cells in patients with atherosclerotic cerebral infarction. Am J Transl Res. 2018; 10(12): 4322-4330.
5. Li Q#*, Ding S#, Wang Y, Xu X*, Shen Z, Fu R, Liu M, Hu C, Zhang C, Cao Q, Wang Y. Age-associated alteration in Th17 cell response is related to endothelial cell senescence and atherosclerotic cerebral infarction. Am J Transl Res 2017; 9(11): 5160-5168.
6. Li Q#*, Ming T#, Wang Y, Ding S, Hu C, Zhang C, Cao Q, Wang Y. Increased Th9 cells and IL-9 levels accelerate disease progression in experimental atherosclerosis. Am J Transl Res 2017; 9(3): 1335-1343.
Contact Information
Email: liqing1300@ustc.edu.cn
Phone: 0551-62283653 (Office)