Born in December 1981, Chief Physician, Head of the Lung and Mediastinum Surgery Subspecialty at the First Affiliated Hospital of USTC (Anhui Provincial Hospital). Recognized as a Distinguished Technical Expert in the third session at the same hospital. Visiting scholar at the University of Duisburg-Essen, Germany, and an expert reviewer for the National Natural Science Foundation of China. Member of various medical committees, including the Thoracic Surgery Committee of the Anhui Branch of the Chinese Medical Association and others related to lung cancer and thoracic surgery.
Education and Work Experience
- Graduated in July 2010 with a Ph.D. in Thoracic Oncology Surgery from Sun Yat-sen University.
- Since July 2010, working in Thoracic Surgery at the First Affiliated Hospital of USTC.
- Visiting scholar at the University of Duisburg-Essen, Germany, from June to September 2017.
Academic Achievements and Impact
Dedicated over ten years to research and teaching in thoracic oncology, supervising five master's students. Awarded the Third Prize for Scientific and Technological Progress in Anhui Province in 2014. Expertise in diagnosing and treating small lung nodules, locally advanced lung cancer, esophageal cancer, and mediastinal tumors. Pioneered single-port thoracoscopic lobectomy, segmentectomy, and pneumonectomy in the province.
Published over 60 academic papers as the first or corresponding author in SCI-indexed and core journals.
Ongoing Projects (Principal Investigator Only)
1. National Natural Science Foundation Project: Mechanism of Acupuncture Intervention on Postoperative Chronic Cough through PKA/PKC Sensitization of TRPV1 Channels (81973643)
- Total Funding: 5.5 million CNY
- Duration: 2020/01-2023/12
2. Anhui Provincial Key Research and Development Project: Clinical Application of Preoperative Planning with Virtual Reality Combined with Intraoperative Fluorescence Imaging for Precise Thoracoscopic Segmentectomy in Early Lung Cancer (202004j07020017)
- Total Funding: 3 million CNY
- Duration: 2020/01-2022/12
Main Research Directions (Enrollment Specialties) and Content
1. Thoracic Surgery
- Research on mechanisms of drug resistance in lung cancer
- Study of precise segmentectomy using fluorescence imaging and preoperative planning
- Research on standardized lymph node dissection in lung cancer
2. Integrated Chinese and Western medicine approaches for preventing and treating complications after lung surgery
Representative Papers (Last Five Years)
1.Mingran Xie, Yongfu Zhu, Shibin Xu, Guangwen Xu, Ran Xiong, Xiaohui Sun and Changqing Liu. A nanoplatform with tumor-targeted aggregation and drug-specific release characteristics for photodynamic/photothermal combined antitumor therapy under near-infrared laser irradiation. Nanoscale. Nanoscale. 2020,12:11497-11509.
2.Gaoxiang Wang, Xianning Wu, Xiaohui Sun, Tian Li, Meiqing Xu, Liangdong Xu, Mingran Xie. Value of N1 Lymph Node Examination in the Prognosis of Patients With pT1-3N0M0 Non-Small Cell Lung Cancer. Front Oncol. 2020,10:603378.
3.Xiong R, Wu H, Wang G, Sun X, Liu C, Xu G, Xie M*. Single-Port Video-Assisted Thoracoscopic Lobectomy for Non-small-Cell Lung Cancer—Learning Curve Analysis. Indian J Surg (2020).
4.Wang G, Li X, Xiong R, Wu H, Xu M, Xie M*. Long-term survival analysis of patients with non-small cell lung cancer complicated with type 2 diabetes mellitus. Thorac Cancer. 2020,11(5):1309-1318.
5.Guang-wen Xu, Ming-ran Xie, Han-ran Wu, Ran Xiong, Cai-wei Li, Shi-bin Xu, Mei-qing Xu & Tian Li. A prospective study examining the impact of uniportal video-assisted thoracic surgery on the short-term quality of life in patients with lung cancer. Thorac Cancer. 2020,11(3):612–618.
6.Xiong R, Sun XX, Wu HR, Xu GW, Wang GX, Sun XH, Xu MQ, Xie MR*. Mechanism research of miR-34a regulates Axl in non-small-cell lung cancer with gefitinib-acquired resistance. Thorac Cancer. 2020,11:156-165.
7.Ming-ran Xie*, Yong-fu Zhu*, Mei-qi Zhou, Sheng-bing Wu, Guang-wen Xu, Shi-bin Xu, Mei-qing Xu. Analysis of factors related to chronic cough after lung cancer surgery. Thorac Cancer. 2019,10(4):898-903.
8.Wu HR, Liu CQ, Xu MQ, Xu GW, Xiong R, Li CW, Xie MR*. Systematic mediastinal lymph node dissection outcomes and conversion rates of uniportal video-assisted thoracoscopic lobectomy for lung cancer. ANZ J Surg. 2019,89(9):1056-60.
9.Yong-fu Zhu, Sheng-bing Wu, Mei-qi Zhou*, Ming-ran Xie*, Ran Xiong, Shi-bin Xu, Guang-wen Xu. Increased expression of TRPV1 in patients with acute or chronic cough after lung cancer surgery. Thorac Cancer. 2019,10(4):988-91.
10.Guang-wen Xu, Han-ran Wu, Ran Xiong, Cai-wei Li, Chang-qing Liu, Mei-qing Xu, Ming-ran Xie*. Value of the preoperative neutrophil-to-lymphocyte ratio as a prognostic factor for long-term survival in postoperative esophageal squamous cell carcinoma patients. Thorac Cancer. 2018,9(12):1707-1715.
11.HanRan Wu, ChangQing Liu, MeiQing Xu, MingFa Guo, ShiBin Xu, MingRan Xie*. Prognostic value of the number of negative lymph nodes in esophageal carcinoma without lymphatic metastasis. Thorac Cancer. 2018,9(9):1129-35.
13.Xie MR, Liu CQ, Guo MF, Mei XY, Sun XH, Xu MQ. Short-term outcomes of minimally invasive Ivor-Lewis esophagectomy for esophageal cancer. Ann Thorac Surg. 2014,97(5):1721-7.
Xie MR, Liu CQ, Guo MF, Mei XY, Sun XH, Xu MQ. Short-term outcomes of minimally invasive Ivor-Lewis esophagectomy for esophageal cancer. Ann Thorac Surg. 2014,97(5):1721-7.
14. Wang Gaoxiang, Xu Meiqing, Xie Mingran*. Research Progress on the Mechanism of Metformin in Lung Cancer. Chinese Journal of Lung Cancer, 2020, 23(4): 282-285.
15. Wang Gaoxiang, Xiong Ran, Wu Hanran, Xu Guangwen, Li Caiwei, Sun Xiaohui, Xu Shibin, Xu Meiqing, Xie Mingran*. Comparative Analysis of Short-term Results of Uniportal and Triportal Thoracoscopic Surgery in Patients with Non-Small Cell Lung Cancer. Chinese Journal of Lung Cancer, 2018, 21(12): 896-901.
16. Xie Mingran, Xu Meiqing, Sun Xiaohui, Xiong Ran, Deng Jie, Wu Hanran, Xu Shibin. Impact of Prognostic Nutritional Index on Postoperative Complications and Prognosis in Patients with Non-Small Cell Lung Cancer. Chinese Journal of Thoracic and Cardiovascular Surgery, 2018, 34(10): 601-605.
17. Li Caiwei, Wu Hanran, Xu Guangwen, Xiong Ran, Xu Meiqing, Xie Mingran*. Analysis of Short- and Long-term Outcomes in Elderly Patients with Esophageal Cancer Post-surgery. Chinese Clinical Oncology, 2018, 45(10): 508-512.
18. Wu Hanran, Li Caiwei, Xiong Ran, Xu Guangwen, Wang Jun, Xu Meiqing, Xie Mingran*. Analysis of Lymph Node Dissection Scope and Transfer Rate in Uniportal Thoracoscopic Lung Surgery. Chinese Journal of Thoracic and Cardiovascular Surgery, 2018, 34(9): 513-517.
19. Xu Shibin, Xu Meiqing, Sun Xiaohui, Deng Jie, Wu Hanran, Xiong Ran, Xie Mingran*. Study on the Correlation between Prognostic Nutritional Index and Postoperative Complications and Long-term Prognosis in Patients with Esophageal Squamous Cell Carcinoma. Chinese Clinical Oncology, 2018, 45(15): 789-794.
20. Wang Gaoxiang, Xiong Ran, Wu Hanran, Xu Guangwen, Li Caiwei, Sun Xiaohui, Xie Mingran*. Prognostic Analysis of Neutrophil/Lymphocyte Ratio in Patients with Resectable Lung Adenocarcinoma. Chinese Journal of Lung Cancer, 2018, 21(8): 588-593.
21. Xie Mingran, Liu Changqing, Guo Mingfa, Sun Xiaohui, Xu Guangwen, Mei Xinyu, Xu Meiqing. Analysis of Short-term Quality of Life after Minimally Invasive Sweet Esophagectomy for Siewert II Type Esophagogastric Junction Adenocarcinoma. Chinese Journal of Thoracic and Cardiovascular Surgery, 2018, 34(7): 385-390.
22. Xiong Ran, Xu Guangwen, Wu Hanran, Li Caiwei, Wang Gaoxiang, Xu Meiqing, Xie Mingran*. Study on the Learning Curve of Uniportal Thoracoscopic Lobectomy for Resectable Lung Cancer. Chinese Journal of Surgery, 2018, 56(6): 447-451.
23. Xu Guangwen, Xiong Ran, Wu Hanran, Li Caiwei, Xu Shibin, Xie Mingran*. Comparative Study on the Impact of Uniportal and Triportal Thoracoscopic Surgery on Short-term Quality of Life in Lung Cancer Patients. Chinese Journal of Surgery, 2018, 56(6): 452-457.
24. Li Caiwei, Xu Meiqing, Xu Guangwen, Xiong Ran, Wu Hanran, Xie Mingran*. Comparative Study of Acute and Chronic Pain after Uniportal and Triportal Thoracoscopic Lung Surgery. Chinese Journal of Lung Cancer, 2018, 21(4): 896-901.
25. Wu Hanran, Liu Changqing, Xu Meiqing, Xiong Ran, Xu Guangwen, Li Caiwei, Xie Mingran*. Application of m-CT Value in Predicting the Malignancy of Clinical Ia Stage Lung Cancer and Precancerous Lesions. Chinese Journal of Lung Cancer, 2018, 21(3): 190-196.
Contact Information
E-mail: xmr1981@ustc.edu.cn
Phone: 0551-62283326