Born in November 1973, Chief Physician, PhD Supervisor. Research focus: Reproductive Medicine. Investigating the mechanisms by which stem cells and platelet-rich plasma repair endometrial fertility damage caused by various factors. She leads projects funded by the National Natural Science Foundation and the Anhui Provincial Natural Science Foundation, and has received an Anhui Provincial Science and Technology Award. She has published over 10 papers.
Contact Information
E-mail: sdl901zsx@163.com
Phone: 13696540912
Education and Work Experience
- 1993–1998: Anhui Medical University, Clinical Medicine, Bachelor’s degree
- 1998–2005: Quanjiao County People’s Hospital, Anhui, Obstetrics and Gynecology, Resident/Attending Physician
- 2005–2008: Anhui Medical University, Reproductive Medicine, Master’s degree
- 2008–2012: Reproductive Center, Anhui Provincial Hospital, Attending Physician
- 2011–2015: Anhui Medical University, Obstetrics and Gynecology, PhD
- 2012–2017: Reproductive Center, Anhui Provincial Hospital, Associate Chief Physician
- 2018–2020: Reproductive and Genetic Hospital, First Affiliated Hospital of USTC, Associate Chief Physician
- 2020–Present: Reproductive and Genetic Hospital, First Affiliated Hospital of USTC, Chief Physician
Academic Achievements and Impact
Dr. Zheng has devoted over 15 years to teaching and research in reproductive medicine, supervising 3 master’s students. She has received one provincial science and technology award and published over 10 papers in academic journals such as Reproductive Medicine, with a total citation count of over ten.
Current Research Projects (Main Responsible Person Only)
Title: Regulatory Network of Wnt/β-catenin Signaling Pathway in Menstrual Blood Stem Cell Repair of Thin Endometrium Fertility
Source: National Natural Science Foundation Project
Funding: 520,000 RMB
Duration: 2020-01 to 2023-12
Main Research Directions (Admissions Major) and Content
Clinical Medicine
1. Reproductive Medicine
- Research on mRNA and small RNA regulatory mechanisms in menstrual blood-derived endometrial stem cell repair of thin endometrium
- Mechanisms of platelet-rich plasma in improving endometrial receptivity in repeated implantation failure
- Mechanisms of chronic endometritis
- Diagnosis and treatment of exosomes and endometrial receptivity
Representative Papers (Last Five Years)
1. Sheng-Xia Zheng, et al. Preclinical researches on menstrual blood-derived stem cells transplantation in the treatment of severe intrauterine adhesions. International Journal of Molecular Medicine. 2018; 41(4): 2201-2212.
2. Bo Xu, Yuan-Wei Zhang, Sheng-Xia Zheng, Xian-Hong Tong, and Yu-Sheng Liu. Expression Profile of MicroRNAs and Their Targeted Pathways in Human Ovaries Detected by Next-Generation Small RNA Sequencing. DNA AND CELL BIOLOGY. 2016; 35(5).
3. Mei-hong Hu, Sheng-xia Zheng, et al. Identification of microRNAs that regulate the MAPK pathway in human cumulus cells from PCOS women with insulin resistance. Reproductive Sciences. 2020; 27(3): 833-844.
4. Zong L, Zheng S, et al. Integrated Transcriptomic Analysis of the miRNA–mRNA Interaction Network in Thin Endometrium. Front. Genet. 2021; 12:589408.
5. Zheng Shengxia, et al. Observation of pregnancy outcomes in patients with chronic endometritis and repeated implantation failure treated with intrauterine perfusion. Practical Medicine Journal. 2019; 35(15): 2434-2437.
6. Zheng Shengxia, et al. Effects of intrauterine G-CSF combined with traditional Chinese medicine on uterine blood circulation and pregnancy outcomes in patients with kidney deficiency and blood stasis type thin endometrium infertility. Modern Journal of Integrated Traditional Chinese and Western Medicine. 2019; 28(23): 2556-2559.
7. Mei-hong Hu, Zheng Shengxia, et al. Effects of tubal ligation and embryo transfer interval on pregnancy outcomes. Anhui Medical. 2019; 40(08): 906-908.
8. Peng Cheng, Zheng Shengxia, et al. Efficacy of simple uterine expansion combined with hyaluronic acid gel in preventing recurrence of moderate to severe intrauterine adhesions. Anhui Medical. 2017; 38: 1273-1275.
9. Zong Lu, Zheng Shengxia, et al. Analysis of hematological indicators in patients with recurrent miscarriage. Journal of Wannan Medical College. 2019, Issue 6.