Professor, Chief Physician, PhD Supervisor, and Postdoctoral Mentor. Recipient of the State Council's Special Government Allowance, National Famous Doctor • Excellent Role Model, Heilongjiang Provincial Model Worker, and the first Longjiang Famous Doctor awards. Has undertaken and led six National Natural Science Foundation projects, three national key R&D plans by the Ministry of Science and Technology, the Ministry of Education's Innovation Team Development Plan, the Ministry of Education's New Century Excellent Talents Support Program, Heilongjiang Provincial Natural Science Foundation, Heilongjiang Provincial Outstanding Youth Fund, and the Heilongjiang Provincial University Science and Technology Innovation Team Support Plan. Published nearly 200 professional academic papers as the first and corresponding author.
Main Research Areas (Recruitment Fields) and Content
Clinical Medicine
1. Surgery
Diagnosis and treatment of common and frequently occurring diseases in general surgery
Research on the mechanisms of occurrence, metastasis, recurrence, and drug resistance reversal in hepatobiliary tumors
Studies on minimally invasive, comprehensive, and immunotherapy treatments for hepatobiliary tumors, as well as organ transplantation
Representative Papers
1.Cheng C, Zha Q, Sun L, Cui T, Guo X, Xing C, Chen Z, Ji C, Liang S, Tao S, Chu J, Wu C, Chu Q, Gu X, Zhang N, Fu Y, Deng S, Zhu Y, Wang J, Liu Y, Liu L. VCP downstream metabolite glycerol-3-phosphate (G3P) inhibits CD8+T cells function in the HCC microenvironment. Signal Transduct Target Ther. 2025 Jan 24;10(1):26.（corresponding author）
2.Guo X, Cui T, Sun L, Fu Y, Cheng C, Wu C, Zhu Y, Liang S, Liu Y, Zhou S, Li X, Ji C, Ma K, Zhang N, Chu Q, Xing C, Deng S, Wang J, Liu Y, Liu L. A STT3A-dependent PD-L1 glycosylation modification mediated by GMPS drives tumor immune evasion in hepatocellular carcinoma. Cell Death Differ. 2025 May;32(5):944-958.（corresponding author）
3.Zhai F, Pan G, Xue L, Cheng C, Wang J, Liu Y, Liu L. PRDM16 Induces Methylation of FLT3 to Promote FLT3-ITD Signaling and Leukemia Progression. Cancer Res. 2025 Feb 1;85(3):535-550.（corresponding author）
4.Fu Y, Guo X, Sun L, Cui T, Wang J, Liu Y, Liu L. Exploring the Interplay of Diet, Obesity, Immune Function, and Cancer. Cancer Discov. 2024 Nov 1;14(11):2047-2050.（corresponding author）
5.Liu Y, Xun Z, Ma K, Liang S, Li X, Zhou S, Sun L, Liu Y, Du Y, Guo X, Cui T, Zhou H, Wang J, Yin D, Song R, Zhang S, Cai W, Meng F, Guo H, Zhang B, Yang D, Bao R, Hu Q, Wang J, Ye Y, Liu L. Identification of a tumour immune barrier in the HCC microenvironment that determines the efficacy of immunotherapy. J Hepatol. 2023 Apr;78(4):770-782.（corresponding author）
Contact Information
E-mail: liulx@ustc.edu.cn
Phone: 0551-62284121