Research Interests
Quorum sensing and biofilm development in major pathogenic bacteria and their pathogenic mechanisms.
Regulation of bacterial cellular behavior by non-coding small RNAs.
Position
Professor and Ph.D. Supervisor
Ph.D. in Microbiology, Michigan State University, USA
Researcher at the National Laboratory for Physical Sciences at the Microscale, Hefei
Research Interests
Quorum sensing and biofilm development in major pathogenic bacteria and their pathogenic mechanisms.
Regulation of bacterial cellular behavior by non-coding small RNAs.
For more details, please visit the lab homepage: http://sunlab.ustc.edu.cn
Current Research Projects
1. Project Title: Tuberculosis Target Research
Major Special Project for the Prevention and Treatment of AIDS, Viral Hepatitis, and Other Major Infectious Diseases
Approval Number: 2008ZX10003-006
Duration: 2008.10-2010.12
Funding: 3.15 million RMB
2. Project Title: Pathogenic Mechanism, Rapid Diagnosis, and Novel Drug Research of Mycobacterium tuberculosis
Important Direction Project of the Knowledge Innovation Program of the Chinese Academy of Sciences
Total Funding: 7 million RMB
Project Number: KSCX2-YW-R-164
Duration: 2009.6-2011.5
Funding: 600,000 RMB
3. Project Title: Functional Analysis of Non-coding Small RNAs in Staphylococcus aureus
General Program of the National Natural Science Foundation
Approval Number: 30970118
Duration: 2010.1-2012.12
Funding: 400,000 RMB
Representative Publications
1.Shang, F., T. Xue, H. Sun, L. Xing, S. Zhang, Z. Yang, L. Zhang, and B. Sun (2009). The Staphylococcus aureus GGDEF domain-containing protein, GdpS, influences protein A gene expression in a cyclic diguanylic acid-independent manner. Infect. Immun. 77:2849-2856.
2.Xue, T., L. Zhao, H. Sun, X. Zhou, and B. Sun (2009). LsrR binding-site recognition and regulatory characteristics in Escherichia coli AI-2 quorum sensing. Cell Res. 19:1258-1268.
3.Zhou, X., X. Meng, and B. Sun (2008). An EAL domain protein and cyclic AMP contribute to the interaction between the two quorum sensing systems in Escherichia coli. Cell Res. 18:937-948.
4.Sun, B., B. M. Griffin, H. L. Ayala-del-Río, S. A. Hashsham, and J. M. Tiedje (2002). Microbial dehalorespiration with 1,1,1-trichloroethane. Science 298:1023-1025.
Contact Information
Phone: 86-551-63606748
Fax: 86-551-63607438
Email: sunb@ustc.edu.cn