Name:

Xing Liu

Address:

443 Huangshan Road, Hefei, Anhui 230027

Tel:

86-551-63607141

Fax:

86-551-63607141

E-mail:

xing1017@ustc.edu.cn

Lab website

http://lcd.ustc.edu.cn/professor6.html

ResearcherID

http://www.researcherid.com/rid/H-2989-2018

EDUCATION AND RESEARCH EXPERIENCE

RESEARCH INTERESTS

Chemical biology of mitosis

Cell division control on organoids

Super-resolution imaging

SELECTED PUBLICATIONS

1. Liu S, Yuan X, Gui P, Liu R, Durojaye O, Hill DL, Fu C, Yao X*, Dou Z*, Liu X*. Mad2 promotes Cyclin B2 recruitment to the kinetochore for guiding accurate mitotic checkpoint. EMBO Rep. 23(6):e54171. (2022)

2. Song X^#, Yang F^#, Liu X^#, Xia P^#, Yin W, Wang Z, Wang Y, Yuan X, Dou Z, Jiang K, Ma M, Hu B, Zhang R, Xu C, Zhang Z, Ruan K, Tian R, Li L, Liu T, Hill DL, Zang J*, Liu X*, Li J*, Cheng J*, Yao X*. Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis. Nat Chem Biol. 17(12):1314-1323. (2021) (Highlighted by Nature Chemical Biology)

3. Xu L^#, Ali M^#, Duan W^#, Yuan X*, Garba F, Mullen M, Sun B, Poser I, Duan H, Lu J, Tian R, Ge Y, Chu L, Pan W, Wang D, Hyman A, Green H, Li L, Dou Z*, Liu D*, Liu X*, Yao X*. Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation. Cell Rep. 36(2):109343. (2021)

4. Tang R^#, Jiang Z^#, Chen F^#, Yu W, Fan K, Tan J, Zhang Z, Liu X*, Li P, Yuan K*. The Kinase Activity of Drosophila BubR1 Is Required for Insulin Signaling-Dependent Stem Cell Maintenance. Cell Rep. 31(12):107794.(2020)

5. Liu X, Liu X, Wang H, Dou Z, Ruan K, Hill DL, Li L, Shi Y, Yao X*. Phase separation drives decision making in cell division. J Biol Chem. 295(39):13419-13431. (2020) Review. (Recommended by F1000)

6. Huang Y^#, Lin L^#, Liu X^#, Ye S^#, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang Y, Zhang J, Yang Z, Liu X, Yang Z, Zang J, Teng M, Wang Z, Ruan K, Ding X, Li L, Cleveland DW, Zhang R*, Yao X*. BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res. 29(7):562-578. (2019) (Highlighted by Cell Research)

7. Akram S^#, Yang F^#, Li J^#, Adams G, Liu Y, Zhuang X, Chu L, Liu X, Emmett N, Thompson W, Mullen M, Muthusamy S, Wang W, Mo F*, Liu X*. LRIF1 interacts with HP1α to coordinate accurate chromosome segregation during mitosis. J Mol Cell Biol. 10(6):527-538. (2018)

8. Yuan X, Yao PY, Jiang J, Zhang Y, Su Z, Yao W, Wang X, Gui P, Mullen M, Henry C, Ward T, Wang W, Brako L, Tian R, Zhao X, Wang F, Cao X, Wang D, Liu X*, Ding X*, Yao X*. MST4 phosphorylates ACAP4 to orchestrate apical membrane remodeling during gastric acid secretion. J Biol Chem. 292(39):16174-16187. (2017)

9. Mo F^#, Zhuang X^#, Liu X*, Yao PY, Qin B, Su Z, Zang J, Wang Z, Zhang J, Dou Z, Tian C, Teng M, Niu L, Hill DL, Fang G, Ding X, Fu C, Yao X*. Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation. Nat Chem Biol. 12(4):226-32. (2016) (Highlighted by Nature Chemical Biology)

10. Zhou J^#, Liu H^#, Zhou S, He P, Liu X*. Adaptor protein APPL1 interacts with EGFR to orchestrate EGF-stimulated signaling. Sci Bull. 61(19): 1504-1512. (2016)

11. Dou Z^#, Liu X^#, Wang W, Zhu T, Wang X, Xu L, Abrieu A, Fu C, Hill DL, Yao X*. Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment. Proc Natl Acad Sci U S A. 112(33):E4546-55. (2015)

12. Liu X^#, Song Z^#, Huo Y, Zhang J, Zhu T, Wang J, Zhao X, Aikhionbare F, Zhang J, Duan H, Wu J, Dou Z, Shi Y and Yao X*. Chromatin protein HP1 interacts with the mitotic regulator borealin protein and specifies the centromere localization of the chromosomal passenger complex. J Biol Chem. 289(30):20638-49. (2014)